Its gives a cooling and soothing effect on the skin especially when your skin is irritated. Soothes the irritation of the most common skin rashes. Absorbs quickly and leaves a fresh and natural feel. Calamine lotion has been used to relieve itchiness and discomfort caused by chicken pox, minor skin rashes, insect bites, measles, eczema, sunburn, poison ivy and other minor skin conditions. Calamine lotion absorbs excess oil which helps you keep away problems like pimples, acne, dark spots, blackheads, whiteheads and patchy skin.